Dimers.com provides weekly NFL picks straight up as part of our NFL Picks coverage.
Week 16 of the NFL season is upon us, and we've used our sophisticated predictive analytics model to give you straight up NFL picks for all 16 games this week.
Secure an edge in NFL pick 'em contests with our data-driven NFL picks for Week 16 of the 2023 NFL season. These picks are based on over 10,000 simulations of each NFL game.
There are 16 games scheduled for Week 16 of the 2023 NFL season, beginning with the New Orleans Saints playing the Los Angeles Rams on Thursday night and concluding with the Baltimore Ravens facing the San Francisco 49ers on Monday night.
These straight up picks for Week 16 are sponsored by Bet365, which has an outstanding Bet $5, Get $150 in Bonus Bets promo for new customers.
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See below for a full list of each team's chances of winning in Week 16 of the NFL.
Straight Up NFL Picks – Week 16
Here are our Week 16 NFL predictions, which show how likely it is that each NFL team will win its game this week.
The Saints take on the Rams at SoFi Stadium on Thursday to start Week 16. According to our NFL model, the Rams have a 65% chance of winning, while the Saints have a 35% chance.
When looking at player props for the opening game of Week 16, our model projects Chris Olave (WR) as the most likely player from the Saints to score the first TD in the game with a probability of 10.1%, while Kyren Williams (RB) is the most likely from the Rams at 14.8%.
New Orleans Saints vs. Los Angeles Rams is at SoFi Stadium on Thursday, December 21 at 8:15pm EST.
All times stated in this article are in Eastern Standard Time (EST).
In this week's game between the Bengals and the Steelers, Cincinnati is more likely to win. Our prediction model gives the Bengals a 65% chance of winning. On the other hand, there is a 35% chance that the Steelers will win.
Cincinnati Bengals vs. Pittsburgh Steelers is at Acrisure Stadium on Saturday, December 23 at 4:30pm.
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We are picking the Bills to win their game against the Chargers this week, with our trusted NFL model projecting an 82% win probability for the road team. The Chargers have a 18% chance of winning.
If you're looking to bet on this clash, Bet365 has the Chargers listed as +12 underdogs, whilst the Bills' moneyline odds are at -625.
Buffalo Bills vs. Los Angeles Chargers is at SoFi Stadium on Saturday, December 23 at 8:00pm.
According to our predictive analytics model, the Seahawks are the team to beat in this game, with their win probability at 64%. The Titans, on the other hand, have a 36% chance of winning.
Seattle Seahawks vs. Tennessee Titans is at Nissan Stadium on Sunday, December 24 at 1:00pm.
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The Colts have a 61% chance of winning on Sunday afternoon, compared to the Falcons' 39% chance of victory. This makes the Indianapolis Colts our pick to win at Mercedes-Benz Stadium.
Indianapolis Colts vs. Atlanta Falcons is at Mercedes-Benz Stadium on Sunday, December 24 at 1:00pm.
The Texans are favored to win here, with our model giving them a 60% chance, while the Browns enter the weekend with a 40% chance of securing a win at NRG Stadium.
When it comes to betting on this game, Bet365 has the Browns' moneyline odds set at +120, with the home team Texans listed as -2.5 favorites.
Cleveland Browns vs. Houston Texans is at NRG Stadium on Sunday, December 24 at 1:00pm.
After 10,000 simulations of Packers vs. Panthers this Sunday, our model projects the Packers as the more likely winners with a probability of 73%. Their opponents the Panthers have a 27% chance of getting the win at home.
Green Bay Packers vs. Carolina Panthers is at Bank of America Stadium on Green Bay, December 24 at 1:00pm.