NFL Week 16 betting odds: Moneylines, spreads and Over/Unders
NFL Week 16 betting odds: Moneylines, spreads and Over/Unders

Heading into Monday Night Football, favorites have gone 12-3 straight up (SU) and against the spread (ATS) in Week 15 – a nice bounceback after going 7-8 SU and 4-10-1 ATS the week prior.

The largest margin of victory was the'Las Vegas Raiders'(6-8) embarrassing the Los Angeles Chargers'(5-9) with a 63-21 victory as 2.5-point home favorites on Thursday Night Football, and the biggest upset of the week was the'Tampa Bay Buccaneers'(7-7) stunning the'Green Bay Packers'(6-8) as 4.5-point underdogs in a 34-20 shocker at Lambeau on Sunday.

Week 16 features 4 days of football, including 10 games on Christmas Eve and 3 on Christmas Day.

The'New Orleans Saints'(7-7) and'Los Angeles Rams'(7-7) kick off the week with a TNF showdown in Inglewood.

  
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