NFL Week 1 Odds, Picks & Predictions: Browns vs. Panthers (2022)
NFL Week 1 Odds, Picks & Predictions: Browns vs. Panthers (2022)

Here is our preview and best bet for the 2022 NFL Week 1 game between the Browns vs. Panthers.

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The Carolina Panthers’ acquisition of former Cleveland Browns starting QB Baker Mayfield provides this contest with a degree of intrigue it would otherwise be lacking. Mayfield's recent comments only add intrigue to the matchup, and this contest has quickly become one of the most compelling of the Week 1 slate.

  
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