49ers vs Vikings Prediction, Odds & Best Prop Bets: NFL, Week 7 MNF
49ers vs Vikings Prediction, Odds & Best Prop Bets: NFL, Week 7 MNF

The San Francisco 49ers visit U.S. Bank Stadium to take on the Minnesota Vikings on Oct. 23. Kickoff is scheduled for 8:15pm EDT in Minneapolis.

The 49ers are betting favorites in this Week 7 matchup, with the spread sitting at -6.5 (-115).

The 49ers vs. Vikings Over/Under is 44 total points for the game.

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49ers vs. Vikings Prediction

Based on recent trends, the winning team model predicts the 49ers will win this Week 7 game with 71.0% confidence.

Based on recent against-the-spread trends, the model predicts the Vikings will cover the spread with 55.0% confidence.

Both predictions factor in up-to-date player injuries for both the 49ers and Vikings, plus offensive & defensive matchups, recent games and key player performances this season.


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Best 49ers Player Prop Bets Today

We’ve highlighted some favorite NFL player prop bets for 49ers players this Week 7 game, looking at profitable historical betting trends:

  • George Kittle has hit the Longest Reception Over in 13 of his last 16 games (+9.55 Units / 51% ROI)
  • Jauan Jennings has hit the Receiving Yards Over in 11 of his last 14 games (+7.70 Units / 49% ROI)
  • Christian McCaffrey has hit the Longest Rush Over in his last 7 away games (+7.00 Units / 89% ROI)
  • Christian McCaffrey has hit the Carries Under in 8 of his last 9 games (+6.95 Units / 57% ROI)
  • Deebo Samuel has hit the Longest Reception Under in 7 of his last 8 games (+5.40 Units / 51% ROI)

Best Vikings Player Prop Best Bets Today

And here are some top NFL player prop bets for Vikings players for this matchup, looking at profitable historical betting trends:

  • Kirk Cousins has hit the Pass Attempts Over in 13 of his last 16 games (+9.60 Units / 53% ROI)
  • K.J. Osborn has hit the Longest Reception Under in 12 of his last 16 games (+7.00 Units / 35% ROI)
  • Justin Jefferson has hit the Receiving Yards Over in 10 of his last 14 games (+5.65 Units / 34% ROI)
  • T.J. Hockenson has hit the Receptions Over in 8 of his last 10 games (+5.45 Units / 42% ROI)
  • T.J. Hockenson has hit the Longest Reception Under in 9 of his last 12 games (+5.00 Units / 32% ROI)

  • The San Francisco 49ers have hit the 4Q Moneyline in 14 of their last 20 games (+10.45 Units / 30% ROI)
  • The San Francisco 49ers have hit the 2H Moneyline in 15 of their last 20 games (+9.10 Units / 22% ROI)
  • The San Francisco 49ers have covered the 2H Spread in 14 of their last 20 games (+8.85 Units / 41% ROI)
  • The San Francisco 49ers have hit the 2Q Game Total Over in 14 of their last 20 games (+7.25 Units / 32% ROI)
  • The San Francisco 49ers have covered the 4Q Spread in 13 of their last 20 games (+4.90 Units / 22% ROI)

  • The Minnesota Vikings have hit the 2H Game Total Over in 12 of their last 18 games (+5.40 Units / 27% ROI)
  • The Minnesota Vikings have hit the 3Q Game Total Over in 12 of their last 18 games (+5.15 Units / 24% ROI)
  • The Minnesota Vikings have hit the 4Q Moneyline in 10 of their last 18 games (+4.20 Units / 19% ROI)
  • The Minnesota Vikings have hit the 4Q Game Total Under in 7 of their last 10 games at home (+3.60 Units / 31% ROI)
  • The Minnesota Vikings have covered the 4Q Spread in 11 of their last 18 games (+3.25 Units / 16% ROI)

49ers Against the Spread (ATS) Record

Against the spread this NFL season, the 49ers went 4-1 (+2.9 Units / 44.27% ROI).

  • 49ers are 5-1 when betting on the Moneyline for +0.45 Units / 1.69% ROI
  • 49ers are 3-2 when betting the Over for +0.8 Units / 12.12% ROI
  • 49ers are 2-3 when betting the Under for -1.3 Units / ROI

Vikings Against the Spread (ATS) Record

Against the spread this NFL season, the Vikings went 2-3 (-1.3 Units / -19.7% ROI).

  • Vikings are 2-4 when betting on the Moneyline for -3.2 Units / -35.96% ROI
  • Vikings are 1-5 when betting the Over for -4.5 Units / -68.18% ROI
  • Vikings are 5-1 when betting the Under for +3.9 Units / 59.09% ROI

San Francisco 49ers: Keys to the Game vs. the Minnesota Vikings

The 49ers are 8-3 (.727) vs top 10 offenses since the 2021 season — tied for best in NFL; League Avg: .346.

The 49ers are undefeated (3-0) when committing less than 60 yards in penalties this season — tied for best in NFL; League Avg: .473.

The 49ers are 7-2 (.778) when passing for 250 or more yards since the 2022 season — fourth-best in NFL. The Vikings have allowed 253.4 passing yards per game since the 2022 season — second-worst in NFL.

The 49ers are 16-3 (.842) when forcing 1 or more turnovers since the 2022 season — second-best in NFL. The Vikings have turned the ball over 36 times since the 2022 season — tied for third-most in NFL.

Minnesota Vikings: Keys to the Game vs. the San Francisco 49ers

The Vikings were undefeated (9-0) when within 7 points at the two minute warning in the 2022 season — best in NFL; League Avg: .492.

The Vikings were undefeated (9-0) when converting 55% or more of its red zone chances into touchdowns in the 2022 season — tied for best in NFL; League Avg: .577.

The Vikings were undefeated (4-0) after a loss in the 2022 season — tied for best in NFL; League Avg: .463.

The Vikings were undefeated (9-0) when leading at the end of the first half in the 2022 season — tied for best in NFL; League Avg: .696.

Additional Matchup Notes for San Francisco 49ers vs. Minnesota Vikings

  
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