The UCF Knights attempt to get off to a 2-0 start for the sixth consecutive season when they host the Louisville Cardinals on Friday. UCF (1-0) opened the 2022 campaign with a 56-10 home victory against South Carolina State, while Louisville (0-1) suffered a 31-7 loss at Syracuse in its opener. The Cardinals defeated the Knights 42-35 at home last year to take a 2-1 lead in the all-time series. Kickoff from FBC Mortgage Stadium in Orlando, Fla. is set for 7:30 p.m. ET.
The Knight s are 6.5-point favorites in the latest UCF vs. Louisville odds from Caesars Sportsbook, while the over/under for total points scored is 61.5. (See the'latest college football lines for all of this week's games on our college football odds page.)
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