The Houston Astros (86-72) and Seattle Mariners (85-72) meet for the Wednesday finale of a key 3-game AL West series. First pitch at T-Mobile Park is slated for 9:40 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Mariners odds and make our expert MLB picks and predictions for the best bets.
Season series: Mariners lead 9-3
Houston took the series opener 5-1 and then dropped a 6-2 decision Tuesday. The Astros are just 1-4 over their last 5 games and 2-6 across their last 8.
Seattle had won 4 straight games against Houston before Monday’s setback. In winning 9-of-12 from the Astros so far, the Mariners have won a season series against Houston for the 1st time since 2018.