College Football Week 1 Odds, Picks & Prediction: Notre Dame vs. Ohio State (9/3)
College Football Week 1 Odds, Picks & Prediction: Notre Dame vs. Ohio State (9/3)

Let’s take a look at the College Football Week 1 odds, picks, and predictions for this week’s prime time game: Notre Dame vs. Ohio State.

Check out our other Week 1 game previews:

  • New Mexico State vs. Minnesota
  • Georgia State vs. South Carolina
  • Nevada vs. Texas State
  • Western Kentucky vs. Hawaii
  • North Carolina State vs. East Carolina
  • Clemson vs. Georgia Tech
  • Boise State vs. Oregon State
  • Arizona vs. San Diego State
  • Utah State vs. Alabama
  • Middle Tennessee vs. James Madison
  • Cincinnati vs. Arkansas
  • Florida State vs. LSU
  • Utah vs. Florida
  • Colorado State vs. Michigan
  • Rice vs. USC
  • Oregon vs. Georgia
  • Louisiana-Monroe vs. Texas

The Buckeyes are a 17-point favorite at home as of this writing, and their offense will obviously be hard for the Fighting Irish to slow down. But I wouldn't touch the line unless it dips below that 17 mark, and I'd focus more on the OVER. The number is at 59 right now, which appears excessively low to me considering QB CJ Stroud, RB TreVeyon Henderson and WR Jaxon Smith-Njigba lead an Ohio State offense that could put up 45 alone against most teams. The OVER has hit in 13 of the last 19 Ohio State games, but it's also 7-2 in Notre Dame's last nine games against the Big Ten.

  
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