2022 AFC South Title Odds, Picks & Predictions:'Colts Are the Favorites
2022 AFC South Title Odds, Picks & Predictions:'Colts Are the Favorites

The new-look Colts lead all AFC South teams at -140 to win the division. After a bad collapse at the end of the season, the Colts traded away QB Carson Wentz. Knowing their window for success is still open, Indy opted to trade for long-time veteran Matt Ryan.

The 37-year-old provides some much-needed stability and experience to the Colts QB room. Between Ryan and breakout star Jonathan Taylor, Indy is looking to end the Colts’ seven-year division title drought. 

The defending division champion Titans are second in line at +180. The back-to-back AFC South champ s are coming off two straight years of playoff disappointment. Despite tremendous regular-season success, the Ryan Tannehill-Derrick Henry-Mike Vrabel trio has not produced significant playoff success.

Tannehill lost his best weapon at wide receiver in A.J. Brown after the disgruntled young star requested a trade. The Rams got a haul on draft day from the Eagles for Brown. But, the Titans’ playmaking and explosiveness certainly took a hit with Brown’s departure. 
  
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By OddsJam