The Notre Dame Fighting Irish (0-0) and Ohio State Buckeyes (0-0) tangle in the feature game of the college football Week 1 schedule. The Irish and Buckeyes will kick things off Saturdaybat 7:30 p.m. ET (ABC) at venerable Ohio Stadium in Columbus, Ohio. Below, we analyze Tipico Sportsbook’s lines around the Notre Dame vs. Ohio State odds; check back for our college football picks, predictions and bets.
Notre Dame ranked 20th in scoring (35.2 points per game) and 15th in scoring defense in a 2021 season that saw it go 11-2. ND lost to Cincinnati in the regular season and Oklahoma State in the Fiesta Bowl. The Irish open this season with a new coach as former Ohio State LB Marcus Freeman takes over for Brian Kelly, who led ND from 2010-21 before leaving for LSU.
Ohio State also went 11-2 in 2021. The Buckeyes suffered regular-season losses to Oregon and Michigan. QB C.J. Stroud returns as the signal caller for an OSU offense which last year led the nation in scoring at 45.7 PPG.
Notre Dame is No. 5 and Ohio State is No. 2 in the AFCA Coaches Poll powered by USA TODAY Sports. Stream select live college football games and full replays: Get ESPN+