:format(webp)/cdn.vox-cdn.com/uploads/chorus_image/image/71282826/usa_today_18860894.0.jpg "NFL preseason 2022: Which 49ers, Texans starters will play, expected inactives for Week 3")
The San Francisco 49ers and Houston Texans will wrap up their preseason Thursday night at NRG Stadium in Houston. 49ers quarterback Trey Lance will get the start and it's a good chance to see him in action before your fantasy football drafts. Here's a deeper look at the matchup and who might play in Thursday's game, which will be televised on Amazon Prime Network at 8 p.m. ET. The 49ers are three-point favorites on DraftKings Sportsbook.
Houston Texans
Davis Mills, the projected starting quarterback, played a half and went 10-for-17 for 96 yards and a touchdown in Houston's 24-20 win over the Los Angeles Rams. Rookie running back Dameon Pierce didn't play and may have done enough in the preseason opener to earn the starting spot in the Texans backfield. Marlon Mack had eight carries for 29 yards and seems to have wrapped up the No. 2 spot at running back.
Observations from Monday's practice for the #Texans including:
-Dameon Pierce. Is he RB1?
-Christian Harris update
-Kenyon Green, a starter?
-Davis Mills' best practice?https://t.co/nt25IyHdqm– Jonathan M Alexander (@jonmalexander) August 22, 2022