OddsJam's NFL experts take you through the betting odds, picks and predictions for this matchup between the Buffalo Bills and the Los Angeles Rams. This game is set to kick off on September 8, 2022. The Los Angeles Rams are at home for this game.
Buffalo Bills vs. Los Angeles Rams Betting Odds
The Buffalo Bills visit the Los Angeles Rams for this NFL matchup on September 8, 2022. Kickoff for Th ursday's game is 8:20 p.m. ET / 5:20 p.m. PT.
The Buffalo Bills are favored at -134 moneyline odds on FanDuel. The Los Angeles Rams are +114 underdogs on the moneyline in this matchup vs. the Buffalo Bills and +2.5 on the point spread at -110 odds.