OddsJam's NFL experts take you through the betting odds, picks and predictions for this NFL preseason matchup between the Buffalo Bills and the Carolina Panthers. This game is set to kick off on August 26, 2022. The Carolina Panthers are at home for this game in Week 3 of the NFL preseason.
Buffalo Bills vs. Carolina Panthers Betting Odds
The Buffalo Bills visit the Carolina Panthers for this NFL matchup on August 26, 2022. Kickoff for Friday's game is 7:00 p.m. ET / 4:00 p.m. PT.
The Carolina Panthers are favored at -240 moneyline odds on DraftKings. The Buffalo Bills are +200 underdogs on the moneyline in this matchup vs. the Carolina Panthers and +6 on the point spread at -110 odds.