All six wild-card round games this weekend are rematches of games played in the regular season. Read on for our NFL best bets of Wild Card Weekend.
San Francisco's Brock Purdy looks to keep his winning streak going to start his career, while another rookie quarterback, Miami's Skylar Thompson, is also in line to make his first playoff start.
Meanwhile, Tom Brady is no stranger to postseason football, as he has numerous playoff records for quarterbacks. However, he finds himself a home underdog in the playoffs for just the seco nd time, if you counted when the Tampa Bay Buccaneers played in Raymond James Stadium in the Super Bowl.
Here are our best NFL bets for Wild Card Weekend (odds via WynnBet, BetMGM, DraftKings Sportsbook, and Caesars Sportsbook; pick confidence based on a 1-to-5-star scale).