The San Francisco 49ers (9-4) meet the Seattle Seahawks (7-6) for a Thursday Night Football matchup in Week 15. Kickoff at Lumen Field in Seattle is scheduled for 8:15 p.m. ET (Prime Video). Below, we analyze Tipico Sportsbook’s'lines around the 49ers vs. Seahawks odds, and make our expert NFL picks and predictions.
The 49ers (-3.5) throttled the visiting Tampa Bay Buccaneers by a 35-7 score, but the victory came with a huge price. WR Deebo Samuel suffered ankle and knee injuries in the 1st half, and is unlikely to play with the short turnaround.
QB Brock Purdy outdueled future Hall of Famer QB Tom Brady, and it wasn’t even close actually. Purdy tossed 2 TDs while running for another, and RB Christian McCaffrey totaled 153 total scrimmage yards with 2 scores.
The Seahawks are coming off a disappointing home loss to the Carolina Panthers 30-24 as 4-point favorites. As such, Seattle has failed to cover in its last 4 games, while winning just once during the span.