The Louisville Cardinals (6-3, 3-3 ACC) meet the No. 12 Clemson Tigers (8-1, 6-0) Saturday at Memorial Stadium in Clemson, S.C. Kickoff is scheduled for 3:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Louisville vs. Clemson odds, and make our expert college football picks and predictions.
The Cardinals posted an impressive 34-10 win over James Madison last week, winning and covering for the 4th consecutive game. Louisville’s win also clinched bowl eligibility, and it is now 6-2 against the spread (ATS) in' the last 8 games.
The Tigers were shocked 35-14 on the road against Notre Dame, and it tumbled to No. 10 in the College Football Playoff rankings as a result.
Clemson’s 14 points last week was a season low, as it had 27 or more points in every previous game this season. The Tigers have failed to cover the last 2 games, and they’re 3-5 ATS in the last 8 games.