OddsJam's NFL experts take you through the betting odds, picks and predictions for this NFL preseason matchup between the San Francisco 49ers vs. the Minnesota Vikings on August 20, 2022 in Minnesota. Let’s get ready for the NFL and bet on preseason football!
49ers vs. Vikings Betting Odds
The San Francisco 49ers visit the Minnesota Vikings for this NFL matchup on August 20, 2022. Kickoff for Saturday's game is 7:00 p.m. ET / 4:00 p.m. PT in Minnesota.
The Minnesota Vikings are favored at -180 vs. the San Francisco 49ers. The San Francisco 49ers are +155 underdogs on the moneyline in this matchup and are +3.5 on the point spread at -110 .