49ers vs. Seahawks TNF Prop Bets, Odds: Thursday Night Football
49ers vs. Seahawks TNF Prop Bets, Odds: Thursday Night Footballiv class=”bodyContent col-lg-9 mb-3″>

The Seattle Seahawks host the San Francisco 49ers as the two NFC West rivals battle on Thursday night. The 49ers still sit third in the Super Bowl odds despite their struggles.

The latest Thursday Night Football odds show the 49ers favored in this game. How can we use that spread to help us make the best 49ers vs. Seahawks TNF prop bets?

Jordan Mason has done a great job filling in for Christian McCaffrey this season. Will he add another 80-plus-yard performance to his game log on Thursday?

Geno Smith leads the NFL in passing yards, and he's likely to be playing from behind all night. Is he in for another huge game? And Brandon Aiyuk finally broke out last week. Can he score his first touchdown of the season?

49ers vs. Seahawks player props: Thursday Night Football

Odds as of Wednesday and subject to change.

  • Jordan Mason Ov er 81.5 rushing yards (-110 via bet365) ????
  • Geno Smith Under 252.5 passing yards (-115 via BetMGM) ????
  • Brandon Aiyuk to score a touchdown (+160 via FanDuel) ???

NFL picks made Wednesday; odds subject to change. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Jordan Mason has run for at least 80 yards in four of his five games this season. His worst rushing performance of the year came against the Los Angeles Rams in Week 3, but he still registered 77 yards in that contest.

The tailback is also averaging 5.1 yards per carry this season. So he can hit this number even without a lot of carries on Thursday. He was only given 14 carries last week but averaged 6.4 yards per attempt.

The Seahawks trot out the NFL's 20th-ran ked rush defense. With that in mind, this number should be higher.

The lowest total available is 80.5 at BetMGM, but the over costs -125. Take the higher total for the much better price as part of your NFL predictions for Week 6.

Best odds: -110 via bet365 | Implied probability: 52.38%

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Geno Smith has thrown for at least 284 yards in four consecutive games. He's topped 300 yards twice this season, and he currently leads the league in passing yards. Yet oddsmakers at our best sports betting sites have set his total more than 40 yards lower than his season average.

The 49ers' defense is allowing just 197.0 passing yards per game this season. Only Sam Darnold topped 252.5 passing yards against the unit, while Kyler Murray, Aaron Rodgers, and Matthew Stafford were all held in check.

Smith has benefitted from a weak schedule, and against the Denver Broncos in Week 1 he managed just 171 yards. FanDuel is setting the total at 248.5. The other best sportsbooks are posting 250.5 and 251.5.

BetMGM is featuring the highest number at 252.5, and the price for the Under is comparable enough there.

Best odds: -115 via BetMGM | Implied probability: 53.49%

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Aiyuk has yet to score a touchdown this season, but he's coming off his best performance of the year and gets a favorable matchup. The wideout recorded eight catches for 147 yards last week, and he was clearly Brock Purdy's top target for the first time this season.

The Seahawks are allowing 1.2 passing touchdowns per game, and 1.7 per contest in their last three. The 49ers boast a lot of weapons, but Aiyuk's role in the offense mixed with the price make this the best touchdown play of the game.

Deebo Samuel notched three touchdowns against the Seahawks last season, but the price for him to score in this game is just +115. That's steep considering he's only logged one touchdown this year.

Aiyuk's price ranges from +130 to +160, with the latter clearly providing much better value through FanDuel.

The wideout might be well-positioned to score, but if t hat happens our Mike Spector thinks it will be one of the few passing touchdowns Purdy records. He tells us why in his 49ers vs. Seahawks prediction.

Best odds: +160 via FanDuel | Implied probability: 38.46%

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49ers vs. Seahawks odds

See all of this week's NFL odds and NFL scores.

Thursday Night Football game info

  • Matchup: 49ers vs. Seahawks
  • Kickoff: 8:15 p.m. ET 
  • Where: Lumen Field, Seattle, WA
  • How to watch: Prime Video
  • Weather: 57 degrees, 10% chance of precipitation, wind 9-mph north winds
  • Favorite: 49ers – 3.5 (+100 via Caesars)

NFL betting odds pages

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NFL Defensive Player of the Year Odds NFL Offensive Rookie of the Year Odds NFL Defensive Rookie of the Year Odds
NFL Coach of the Year Odds NFL Comeback Player of the Year Odds NFL Win Totals Odds
NFL Playoff Odds NFL Draft Odds

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