49ers vs Seahawks Picks, Odds: NFL Wild Card Saturday Prediction
49ers vs Seahawks Picks, Odds: NFL Wild Card Saturday Prediction

  • The 49ers are 9.5-point favorites over the Seahawks at most sportsbooks.
  • San Francisco handled Seattle in both regular-season meetings between the NFC West rivals.
  • Brandon Anderson breaks down the matchup and makes his 49ers vs. Seahawks pick below.

The NFL playoffs are finally here, and it starts with finding a 49ers vs. Seahawks pick.

No one expected Brock Purdy and Geno Smith to kick off our NFL postseason, but here we are. Looking at the 49ers vs. Seahawks odds, you wouldn’t think that a seventh-round rookie could be laying 9.5 points, but here we are.

Purdy is Mr. Irrelevant, the final pick from the worst quarterback draft in years. He started the season as a third-string backup who’s now an undefeated starter and Offensive Rookie of the Year Award candidate for the league’s hottest team. Smith was even more irrelevant before setting the Seahawks’ single-season passing record and leading Seattle on a shocking run to the playoffs.

Both quarterbacks make their playoff debut in the Wild Card Round, but one of them will have far more help than the other. The 49ers are near double-digit favorites after owning this regular season matchup and finishing the year on a 10-game win streak.

  
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