When the San Francisco 49ers (6-4) host the New Orleans Saints (4-7) on Sunday, November 27, 2022 at Levi’s Stadium, they will be aiming to extend their three-game winning streak.
49ers vs. Saints Odds
The spread for this matchup is set at 9.5 points, with bookmakers listing the 49ers as the favorites.
As for the moneyline, the 49ers have -390 odds to pick up the win, while the Saints are listed at +320 to claim victory.
Finally, the over/under for the game is set at 43 points.