Last Sunday the San Francisco 49ers were humiliated at home by Patrick Mahomes and the Kansas City Chiefs, losing 44-23. It was the Niners' second defeat in a row and dropped them to 3-4 for the season as they visit the rival Los Angeles Rams. Check out our top 49ers-Rams picks below.
Week 8 is a rematch of January's NFC Championship Game. The Rams got a rare win over the 49ers at SoFi Stadium that weekend, although they continue to struggle against their NFC West rivals in the regular season. San Francisco beat L.A. in each of the p ast seven regular-season matchups, including a 24-9 success in Santa Clara four weeks ago.
While the 49ers were giving up 529 total yards to the Chiefs last week, the Rams were on their bye week. Will a refreshed Los Angeles end the domination of its rivals from north Cal?
Here are our 49ers-Rams picks for Week 8 (odds via Draftkings Sportsbook and PointsBet; pick confidence based on a 1-to-5-star scale).