49ers vs. Patriots best bets, picks and odds | Week 4
49ers vs. Patriots best bets, picks and odds | Week 4

The New England Patriots (1-2) hit the road to play the San Francisco 49ers (1-2) at Levi’s Stadium on Sunday, September 29, 2024, and here are our best bets.

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Best against the spread pick

  • Pick ATS:
    Pick Em
  • San Francisco is 1-2-0 against the spread this season.
  • Entering play this week, New England has one victory against the spread this season.

Best over/under pick

  • Pick OU: Under (40.5)
  • The Patriots have played just one game this season that finished with a combined score over 40.5 points.
  • These teams average 37.3 points per game combined, 3.2 less than this game’s total.
  • These two teams surrender a combined 42 points per game, 1.5 more points than this contest’s total.

Best moneyline bet

  • Moneyline pick: 49ers -599
  • The 49ers have an implied moneyline win probability of 85.7% in this game.
  • San Francisco has won one of the three games it was listed as the moneyline favorite this season (33.3%).
  • The 49ers have never played a game this season with moneyline odds of -599 or shorter.
  • New England has entered the game as an underdog three times this season and won once.
  • The Patriots have not entered a game this season as a bigger underdog on the moneyline than the +425 odds on them winning this game.

How to watch 49ers vs. Patriots

  • When: Sunday, September 29, 2024 at 4:05 p.m. ET
  • Where: Levi’s Stadium in Santa Clara, California
  • TV Info: FOX
  • Live stream: Watch on Fubo! (Regional restrictions may apply)

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