49ers vs Panthers Week 5 Game Info
2022 NFL Regular Season'Game
San Francisco 49ers'(1-2, 0-2 Away) vs.'Carolina Panthers'(1-3, 1-2 Home)
Date:'Sunday, Oct. 9, 2022
Time:'4:05 p.m. ET
Venue:'Bank of America Stadium – Charlotte, NC
Coverage:'CBS
Week 5 of the 2022 NFL season includes a showdown between the San Francisco 49ers and Carolina Panthers. At the time of writing, the 49ers have yet to play their Week 4 matchup against the Los Angeles Rams, leaving time to tell if San Francisco can bounce back from the previous week's loss or if their losing streak grows to two.
Meanwhile, the Panthers continued their early season struggles in the form of a 26-16 loss to the Arizona Cardinals on Sunday. Ball security was one of Carolina's many issues in the loss, highlighted by quarterback Baker Mayfield's pair of intercept ions on the day.
49ers vs Panthers Odds & Spread
Moneyline:'SF: (-215) | CAR: (+180)
Spread:'SF: -4.5 (-108) | CAR: +4.5 (-112)
Total:'40 -Over: (-110) | Under: (-110)
The 49ers enter this contest as the road favorite on the moneyline and spread on FanDuel Sportsbook's odds. This 4:05 p.m. ET clash also features a total of 40, which is the lowest of the projected Week 5 totals.
49ers vs Panthers Prediction & Pick
Both teams may have had their struggles so far, but my money is on the 49ers here. San Francisco has had issues scoring the ball, but its defense allowing a league-low 12.3 points per game has more than made up for it. Meanwhile, Carolina has averaged the ninth-fewest points since Week 2 (18.0) – not exactly encouraging.
The 49ers are a run-heavy team and the fact that the Panthers surrender 134 rushing yards per game (eighth-most) has San Francisco licking its lips. Once the 49ers take the lead, they have the talent to run out the clock, making this game one that the Panthers-favoring bettors might want to avoid.
Final Score Prediction:'49ers: 24 | Panthers: 13< /p>
49ers vs Panthers Betting Trends
– San Francisco is 10-5 straight up in its last 15 games.
– Carolina is 7-3 against the spread (ATS) in its last 10 games against San Francisco.
– The total has hit the under in each of San Francisco's last five games against the NFC.
– The total has hit the under in five of Carolina's last seven games.
49ers vs Panthers Best Bet
Fans expecting a lot of points on the board will be disappointed here. Neither team has shown much offensive flair so far this season, finish ing with fewer than 20 points scored more often than not. Although I do expect the 49ers to score the ball a few times this weekend, the Panthers' offensive struggles will likely result in this game hitting below 40 points.