49ers vs Panthers Expert Picks & Predictions for Week 5 NFL Game
49ers vs Panthers Expert Picks & Predictions for Week 5 NFL Game

The 2022 NFL season is underway and the Week 5 schedule is full of exciting showdowns. One of the more interesting matchups is an NFC clash'between the San Francisco 49ers and Carolina Panthers.

The 49ers are riding a high this week after their huge 24-9 vi ctory over the Los Angeles Rams on Monday Night Football. On the other hand, the Baker Mayfield era has been a disaster for the Panthers, who dropped to 1-3 following a 26-16 loss to the Arizona Cardinals.

Can San Francisco continue showcasing their ability to be Super Bowl contenders this year? Or does Carolina have what it takes to pull off a major upset at home?

Here's what projection models and experts across the industry have to say about the 49ers vs Panthers Week 5 matchup.

49ers vs Panthers Projections

ESPN FPI :'49ers (50.9%)
numberFire:'49ers (63.7%)
FiveThirtyEight:'49ers (70%)
Betting Favorite:'49ers (-6.5)

Projected Winner:'49ers (4)

49ers vs Panthers Expert Picks

ESPN Experts:'49ers (7)
Sports Illustrated Experts:'49ers (5)
CBS Sports Experts:'49ers (7)

Expert Totals:'49ers (19)

When it comes to projections, the four highlighted sources are all backing the 49ers to win. The 19 highlighted experts are also on the same page, unanimously backing San Francisco as well.

There's really no need to overthink this one. The 49ers are the clear-cut better team and shouldn't have any issues with the Panthers, barring a total collapse.