49ers vs. Jaguars odds, line, spread: Proven model reveals NFL picks, predictions for Week 10, 2023
49ers vs. Jaguars odds, line, spread: Proven model reveals NFL picks, predictions for Week 10, 2023

The San Francisco 49ers look to snap their three game losing streak as they head east to face the Jacksonville Jaguars on Sunday afternoon. San Francisco (5-3) enters off a bye after falling to Cincinnati, 31-17 in Week 8. Jacksonville (6-2) also was off in Week 9 but enters on a five game winning streak after defeating Pittsburgh, 20-10. The 49ers won the most recent matchup, 30-10 in 2021.
  
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