49ers vs. Giants NFL Week 3 lines, odds, picks: Thursday Night Football predictions and best bets from proven model
49ers vs. Giants NFL Week 3 lines, odds, picks: Thursday Night Football predictions and best bets from proven model

The San Francisco 49ers (2-0) look to remain perfect when the begin Week 3 of the 2023 NFL season with their home opener against the New York Giants (1-1) on Thursday Night Football. San Francisco opened the campaign with road victories against Pittsburgh and the Los Angeles Rams, scoring 30 points in each contest. New York avoided an 0-2 start to the year by staging the largest comeback of the Super Bowl era in franchise history on Sunday to post a 31-28 win at Arizona.
  
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