49ers vs. Cardinals Week 11 Prediction and Odds – Nov 21, 2022

The Arizona Cardinals face the favored San Francisco 49ers in NFL Week 11 action at Estadio Azteca on Monday, starting at 8:15PM ET.

Dimers' top betting picks for 49ers vs. Cardinals, as well as game predictions, betting odds and projected player stats, are featured below.

 

Who will win 49ers vs. Cardinals?

Using trusted computer power and data, Dimers.com has simulated Monday's 49ers-Cardinals NFL matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the 49ers a 78% chance of getting the W against the Cardinals in Week 11 of the NFL season.

More: 49ers vs. Cardinals Simulated 10,000 Times

49ers vs. Cardinals Current Odds

  • Spread: Cardinals +8 (-107), 49ers -8 (-107)
  • Moneyline: Cardinals +290, 49ers -345
  • Total: Over/Under 43.5 (-107/-107)

  
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By Dimers