An NFC West battle is on tap between the San Francisco 49ers and the Arizona Cardinals at 4:25 p.m. ET on Sunday at Levi's Stadium. San Francisco is 12-4 overall and 7-1 at home, while Arizona is 4-12 overall and 3-4 on the road. The 49ers are ranked first in the NFC West; Arizona is ranked fourth. The 49ers are 10-6 and the Cardinals are 8-8 against the spread this season.
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