49ers vs. Broncos NFL lines, odds, picks: Proven NFL model reveals predictions for a Sunday Night Football Battle
49ers vs. Broncos NFL lines, odds, picks: Proven NFL model reveals predictions for a Sunday Night Football Battle

The San Francisco 49ers (1-1) and the Denver Broncos (1-1) clash in a battle on Sunday Night Football. Kickoff is set for 8:20 p.m. ET from Empower Field. San Francisco is a 1.5-point favorite in the latest 49ers vs. Broncos odds from Caesars Sportsbook, and the over/under for total points scored is 45. Before you make any 49ers vs. Broncos picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2022 NFL season on an incredible 139-102 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model knows San Francisco will look to get their powerful rushing attack going. Kyle Shanahan loves to build his passing game based on an effective ground game. They currently rank fourth in the league in rushing yards per game (182.5) with three touchdowns. In the win over the Seattle Seahawks last week, they ran for 183 yards on 4.2 yards per rush.'

  
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