49ers vs Bears Prediction, Odds & Best Prop Bets – NFL, Week 1
49ers vs Bears Prediction, Odds & Best Prop Bets – NFL, Week 1

The San Francisco 49ers (0-0) visit Soldier Field to take on the Chicago Bears (0-0) on Sep. 11. Kickoff is scheduled for 1:00pm ET in Chicago.

The 49ers are betting favorites in Week 1, with the spread sitting at -6.5 (-115).

The 49ers vs. Bears Over/Under is 40.5 total points for the game.

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49ers vs. Bears Prediction for Week 1

Based on recent trends the model predicts the 49ers will win this Week 1 NFL matchup with 55.0% confidence.

This prediction factors in up-to-date player injuries for both the 49ers and Bears, plus offensive & defensive matchups, recent games and key player performances this season.


Best 49ers Player Prop Bets Today

We’ve highlighted some favorite NFL player prop bets for 49ers players for Week 1, looking at profitable historical betting trends:

  • Deebo Samuel has hit the Receptions Under in 12 of his last 13 games (+10.30 Units / 51% ROI)
  • Jimmy Garoppolo has hit the Completions Under in 11 of his last 14 games (+7.50 Units / 42% ROI)
  • George Kittle has hit the Receptions Under in his last 6 games (+6.00 Units / 74% ROI)
  • Jimmy Garoppolo has hit the Rushing Yards Under in 8 of his last 10 games (+5.25 Units / 40% ROI)
  • Eli Mitchell has hit the Carries Over in 7 of his last 9 games (+4.65 Units / 46% ROI)

Best Bears Player Prop Best Bets Today

And here are some top NFL player prop bets for Bears players for Week 1, looking at profitable historical betting trends:

  • Darnell Mooney has hit the Receptions Over in 6 of his last 7 games at home (+6.65 Units / 77% ROI)
  • Cole Kmet has hit the Receptions Over in 8 of his last 10 games (+5.55 Units / 41% ROI)
  • Justin Fields has hit the TD Passes Under in 7 of his last 10 games (+5.00 Units / 25% ROI)
  • Darnell Mooney has hit the Receiving Yards Over in his last 4 games (+4.00 Units / 87% ROI)
  • David Montgomery has hit the Rushing Yards Under in 6 of his last 8 games (+3.50 Units / 36% ROI)

First Touchdown Scorer Bet for Bears vs 49ers

Player Name 1st TD Odds
Deebo Samuel +450
Elijah Mitchell +600
Trey Lance +900
George Kittle +900
David Montgomery +900

Anytime Touchdown Scorer Bet for Bears vs 49ers

Player Name Anytime TD Odds
Deebo Samuel -110
Elijah Mitchell +115
George Kittle +150
David Montgomery +150
Darnell Mooney +175

Receiving Props: Total Receiving Yards for Bears vs 49ers

Player Name Over Under
Brandon Aiyuk 49.5 -115 49.5 -110
David Montgomery 14.5 -120 14.5 -110
Jauan Jennings 16.5 -115 16.5 -115
Eli Mitchell 8.5 -110 8.5 -115
Kyle Juszczyk 7.5 -110 7.5 -115

Rushing Props: Total Rushing Yards for Bears vs 49ers

Player Name Over Under
Eli Mitchell 61.5 -115 61.5 -110
Trey Lance 38.5 -115 38.5 -110
Justin Fields 33.5 -115 33.5 -115
David Montgomery 55.5 -110 55.5 -115

  • The San Francisco 49ers have hit the 3Q Moneyline in 10 of their last 12 games (+8.50 Units / 53% ROI)
  • The San Francisco 49ers have covered the 3Q Spread in 10 of their last 12 games (+8.10 Units / 59% ROI)
  • The San Francisco 49ers have covered the Spread in 10 of their last 12 games (+7.95 Units / 60% ROI)
  • The San Francisco 49ers have hit the Moneyline in 9 of their last 12 games (+7.70 Units / 31% ROI)
  • The San Francisco 49ers have hit the 1H Game Total Under in their last 6 games (+6.00 Units / 92% ROI)

  • The Chicago Bears have hit the 1Q Game Total Under in 11 of their last 16 games (+7.65 Units / 40% ROI)
  • The Chicago Bears have covered the 2Q Spread in 6 of their last 7 games (+6.05 Units / 78% ROI)
  • The Chicago Bears have scored last in 6 of their last 7 games (+5.90 Units / 76% ROI)
  • The Chicago Bears have hit the 2Q Moneyline in 8 of their last 17 games (+4.60 Units / 25% ROI)
  • The Chicago Bears have hit the 1H Game Total Under in 11 of their last 17 games (+4.35 Units / 23% ROI)

San Francisco 49ers: Keys to the Game vs. the Chicago Bears

The 49ers were 7-0 (1.000) when not throwing an interception last season — tied for best in NFL. The Bears intercepted 8 passes last season — fourth-fewest in NFL.

The 49ers were 9-3 (.750) when forcing 1 or more turnovers last season — tied for ninth-best in NFL. The Bears turned the ball over 28 times last season — tied for third-most in NFL.

The 49ers were undefeated (6-0) when the opposing team converts less than 55% of its red zone chances into touchdowns last season — tied for best in NFL; League Avg: .533.

The 49ers were 1-2 (.333) when the opposing team rushes more than 30 times last season — tied for 3rd-best in NFL; League Avg: .165.

Chicago Bears: Keys to the Game vs. the San Francisco 49ers

  
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