2022 NCAA Tournament odds, lines, spreads: Proven model reveals top Final Four parlay picks

The 2022 NCAA Tournament Final Four takes place on Saturday, with No. 1 Kansas vs. No. 2 Villanova in the day's first matchup at 6:09 p.m. ET. The Jayhawks are 4.5-point favorites in a rematch of the 2018 Final Four and the over-under is 133 in the latest 2022 Final Four odds from Caesars Sportsbook. The nightcap features the first-ever March Madness matchup between No. 2 Duke and No. 8 North Carolina at 8:49 p.m. ET. The Blue Devils are 4.5-point favorites with the over-under at 151 in the 2022 NCAA Tournament odds.

Before you make any colleg e basketball bets or Final Four 2022 parlays, you need to see what the SportsLine projection model has to say.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $1,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns!'

Now, the model has crunched the numbers for Saturday's Final Four, with against-the-spread and over-under picks for both games. A successful parlay of these picks would pay out 12-1!

  
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